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Literature summary extracted from

  • Kim, J.H.; Kim, H.J.; Park, H.W.; Youn, S.H.; Choi, D.Y.; Shin, C.S.
    Development of inhibitors against lipase and alpha-glucosidase from derivatives of monascus pigment (2007), FEMS Microbiol. Lett., 276, 93-98.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.20 butylglycine derivative of monascus pigment produced by Monascus sp. strain KCCM10093 after feeding of the unusual amino acid, low inhibition level Sus scrofa
3.2.1.20 cyclohexylalanine derivative of monascus pigment produced by Monascus sp. strain KCCM10093 after feeding of the unusual amino acid, low inhibition level Sus scrofa
3.2.1.20 additional information amino acid derivatives of the monascus orange pigment containing aminohexanoic acid, citrulline, homocitrulline, homoserine, norvaline, ornithine, or aminobutyric acid are poorly inhibitory, overview Sus scrofa
3.2.1.20 norleucine derivative of monascus pigment produced by Monascus sp. strain KCCM10093 after feeding of the unusual amino acid, low inhibition level Sus scrofa
3.2.1.20 penicillamine derivative of monascus pigment produced by Monascus sp. strain KCCM10093 after feeding of the unusual amino acid, mixed type inhibition pattern Sus scrofa
3.2.1.20 phenylglycine derivative of monascus pigment produced by Monascus sp. strain KCCM10093 after feeding of the unusual amino acid, low inhibition level Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.20 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.20 commercial preparation from pancreas Sus scrofa
-
3.2.1.20 pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.20 4-nitrophenyl alpha-D-glucopyranoside + H2O
-
 Sus scrofa 4-nitrophenol + alpha-D-glucose
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.20 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.20 6.8
-
 assay at Sus scrofa

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.2.1.20 0.0259
-
 penicillamine derivative of monascus pigment
-
 Sus scrofa

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.2.1.20 0.0509
-
-
 Sus scrofa penicillamine derivative of monascus pigment