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Literature summary extracted from

  • Walcheck, B.; Herrera, A.H.; St.Hill, C.; Mattila, P.E.; Whitney, A.R.; De Leo, F.R.
    ADAM17 activity during human neutrophil activation and apoptosis (2006), Eur. J. Immunol., 36, 968-976.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.24.86 N-formyl-L-methionyl-phenylalanine ADAM17 substrates undergo efficient turnover during extended neutrophil activation by N-formyl-L-methionyl-phenylalanine Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.86 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.86 neutrophil
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.86 L-selectin + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.86 p75 tumour necrosis factor receptor + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.86 proTNF-alpha + H2O
-
 Homo sapiens soluble TNF-alpha
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.86 ADAM17
-
 Homo sapiens
3.4.24.86 TACE
-
 Homo sapiens
3.4.24.86 TNF-alpha converting enzyme
-
 Homo sapiens
3.4.24.86 tumor necrosis factor alpha-converting enzyme
-
 Homo sapiens