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Literature summary extracted from

  • Wright, L.C.; Santangelo, R.M.; Ganendren, R.; Payne, J.; Djordjevic, J.T.; Sorrell, T.C.
    Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids (2007), Eukaryot. Cell, 6, 37-47.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.5 additional information Cryptococcus neoformans phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids. During both logarithmic and stationary phases of growth, the physiologically relevant phospholipids, dipalmitoyl phosphatidylcholine (DPPC) and dioleoyl phosphatidylcholine, are taken up and metabolized via PLB1 ?
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Organism

EC Number Organism UniProt Comment Textmining
3.1.1.5 Cryptococcus neoformans
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var. grubii H99 wild-type strain and its PLB1 deletion mutant strain (the _plb1 strain)
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.5 additional information phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids. During both logarithmic and stationary phases of growth, the physiologically relevant phospholipids, dipalmitoyl phosphatidylcholine (DPPC) and dioleoyl phosphatidylcholine, are taken up and metabolized via PLB1 Cryptococcus neoformans ?
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