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Literature summary extracted from
- Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia (2007), Diabetes, 56, 224-230.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.22.36 | medicine | the caspase-1/IL-1beta signaling pathway plays an important role in diabetes-induced retinal pathology, and its inhibition might represent a new strategy to inhibit capillary degeneration in diabetic retinopathy | Mus musculus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.36 | minocycline | - |
Mus musculus |  |
| 3.4.22.36 | tetracycline | - |
Mus musculus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.36 | Mus musculus | - |
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- |
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Release 2023.1 (January 2023)
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