EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.47 | iodoacetamide | - |
Bos taurus | |
3.1.1.47 | additional information | no inactivation by NaF or dithiothreitol | Bos taurus | |
3.1.1.47 | p-bromophenacylbromide | - |
Bos taurus | |
3.1.1.47 | phenylmethylsulfonyl fluoride | - |
Bos taurus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.47 | 0.0876 | - |
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine | - |
Bos taurus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.1.47 | 45000 | - |
1 * 45000, SDS-PAGE | Bos taurus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.47 | Bos taurus | Q29460 and P68401 | gamma-subunit and beta-subunit | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.1.47 | - |
Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.47 | colostrum | the greatest PAF-AH activity is detected on the day of parturition (day 0), after which its activity dramatically decreases and by day 5, the enzyme activity is less than 7% of the level at parturition | Bos taurus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.1.47 | 0.015 | - |
- |
Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.47 | 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O | - |
Bos taurus | 1-O-alkyl-sn-glycero-3-phosphocholine + acetate | - |
? | |
3.1.1.47 | additional information | selectively hydrolyzes oxidatively modified phosphatidylcholine. The purified enzyme does not degrade phospholipids with a long chain fatty acyl group at the sn-2 position | Bos taurus | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.1.47 | ? | 1 * 45000, SDS-PAGE | Bos taurus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.47 | 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase | - |
Bos taurus |
3.1.1.47 | PAF acetylhydrolase | - |
Bos taurus |
3.1.1.47 | PAF-AH | - |
Bos taurus |
3.1.1.47 | platelet activating factor acetylhydrolase | - |
Bos taurus |