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Literature summary extracted from

  • Hermey, G.; Sjogaard, S.S.; Petersen, C.M.; Nykjaer, A.; Gliemann, J.
    Tumor necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members (2006), Biochem. J., 395, 285-293.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.86 expressed in CHO cells Mesocricetus auratus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.86 GM6001 galardin Mesocricetus auratus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.86 Mesocricetus auratus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.86 proTNF-alpha + H2O
-
 Mesocricetus auratus soluble TNF-alpha
-
 ?
3.4.24.86 sorCS1c + H2O member of the vacuolar protein sorting 10p domain family of neuronal type-I receptors Mesocricetus auratus ?
-
 ?
3.4.24.86 sorCS2 + H2O member of the vacuolar protein sorting 10p domain family of neuronal type-I receptors, minor shedding Mesocricetus auratus ?
-
 ?
3.4.24.86 sorCS3 + H2O member of the vacuolar protein sorting 10p domain family of neuronal type-I receptors Mesocricetus auratus ?
-
 ?
3.4.24.86 sorLA + H2O member of the vacuolar protein sorting 10p domain family of neuronal type-I receptors Mesocricetus auratus ?
-
 ?
3.4.24.86 sortilin + H2O member of the vacuolar protein sorting 10p domain family of neuronal type-I receptors, minor shedding Mesocricetus auratus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.86 ADAM17
-
 Mesocricetus auratus
3.4.24.86 TACE
-
 Mesocricetus auratus
3.4.24.86 tumour necrosis factor alpha-converting enzyme
-
 Mesocricetus auratus