Literature summary extracted from

Schweitzer, K.; Decker, E.; Zhu, L.; Miller, R.E.; Mirra, S.S.; Spina, S.; Ghetti, B.; Wang, M.; Murrell, J.
Aberrantly regulated proteins in frontotemporal dementia (2006), Biochem. Biophys. Res. Commun., 348, 465-472.

Application

EC Number	Application	Comment	Organism
3.4.19.12	medicine	UCHL1 is aberrantly regulated in frontotemporal dementia and parkinsonism linked to chromosome 17	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.19.12	Homo sapiens	P09936	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.19.12	additional information	UCHL1 is downregulated in the frontal cortex of frontotemporal dementia and parkinsonism linked to chromosome 17	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.19.12	Nedd-8 + H2O	-	Homo sapiens	?	-	?
3.4.19.12	ubiquitin + H2O	-	Homo sapiens	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.19.12	ubiquitin C-terminal hydrolase L1	-	Homo sapiens
3.4.19.12	UCHL1	-	Homo sapiens

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Release 2023.1 (January 2023)