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Literature summary extracted from

  • Juretic, D.; Motejlkova, A.; Kunovi?, B.; Reki?, B.; Flegar-Mestri?, Z.; Vuji?, L.; Mesi?, R.; Lukac-Bajalo, J.; Simeon-Rudolf, V.
    Paraoxonase/arylesterase in serum of patients with type II diabetes mellitus (2006), Acta Pharm., 56, 59-68.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.2 Ca2+ required Homo sapiens
3.1.8.1 Ca2+ required Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.2 Homo sapiens
-
-
-
3.1.8.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.2 blood serum enzyme activity against the phenylacetate is higher, and phenotype-dependent, only in diabetic patients with type II diabetes mellitus. Less antiatherogenic paraoxonase B allele is more frequent in type II diabetes mellitus than in the healthy population. Their lipid status is more atherogenic, which could indicate a risk of premature atherosclerosis Homo sapiens
-
3.1.8.1 blood serum of patients with type II diabetes mellitus. There are no differences in paraoxonase activities between the gender- and phenotype-matched diabetic and control groups. Less antiatherogenic paraoxonase B allele is more frequent in type II diabetes mellitus than in the healthy population. Their lipid status is more atherogenic, which could indicate a risk of premature atherosclerosis Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.2 phenyl acetate + H2O PON1 activity determined towards the synthetic compounds paraoxon and phenyl acetate reflects no association with markers of oxidative stress Homo sapiens phenol + acetate
-
 ?
3.1.8.1 paraoxon + H2O
-
 Homo sapiens diethylphosphate + 4-nitrophenol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.2 paraoxonase/arylesterase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.2 37
-
 assay at Homo sapiens
3.1.8.1 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.2 8
-
 assay at Homo sapiens
3.1.8.1 8
-
 assay at Homo sapiens