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Literature summary extracted from

  • Rouhana, L.; Wickens, M.
    Autoregulation of GLD-2 cytoplasmic poly(A) polymerase (2007), RNA, 13, 188-199.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.19 additional information cytoplasmic polyadenylation elements and PUF-binding elements are required for repression of GLD-2 mRNA Xenopus laevis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.19 cytoplasm
-
 Xenopus laevis 5737
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.19 Xenopus laevis
-
-
-
2.7.7.19 Xenopus laevis
-
 positive feedback circuit in which translation of isoform GLD-2 mRNA is stimulated by its polyadenylation, thereby reinforcing the switch to polyadenylate and activate batteries of mRNAs
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.19 brain
-
 Xenopus laevis
-
2.7.7.19 cerebellum
-
 Xenopus laevis
-
2.7.7.19 cerebrum
-
 Xenopus laevis
-
2.7.7.19 medulla oblongata
-
 Xenopus laevis
-
2.7.7.19 oocyte
-
 Xenopus laevis
-
2.7.7.19 spinal nerve
-
 Xenopus laevis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.19 ATP + RNA
-
 Xenopus laevis diphosphate + RNA(A)n
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.19 GLD-2
-
 Xenopus laevis
2.7.7.19 PAP
-
 Xenopus laevis
2.7.7.19 poly(A) polymerase
-
 Xenopus laevis