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Literature summary extracted from

  • Riemenschneider, A.; Riedel, K.; Hoefgen, R.; Papenbrock, J.; Hesse, H.
    Impact of reduced O-acetylserine(thiol)lyase isoform contents on potato plant metabolism (2005), Plant Physiol., 137, 892-900.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.47 to decrease the activity of OASTL, potato plants are transformed with the vector pBinAR harboring a cDNA encoding a sequence from either the StOASTL A or the StOASTL B gene in reverse orientation with respect to the cauliflower mosaic virus 35S promoter. THe transgenic approach is used to downregulate specifically the plastidial and cytosolic isoforms in Solanum tuberosum. This approach results in decreased RNA, protein, and enzymatic activity levels. H2S-releasing capacity is also reduced in these lines. The thiol levels in the transgenic lines are, regardless of the selected OASTL isoform, significantly elevated. Levels of metabolites such as serine, O-acetyl-L-Ser, methionine, threonine, isoleucine, and lysine also increase in the investigated transgenic lines Solanum tuberosum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.47 chloroplast
-
 Solanum tuberosum 9507
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.47 O-acetyl-L-Ser + H2S Solanum tuberosum OASTL activity regulates not only Cys de novo synthesis but also its homeostasis L-Cys + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.47 Solanum tuberosum O81154
-
-
2.5.1.47 Solanum tuberosum O81155
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.47 leaf
-
 Solanum tuberosum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.47 O-acetyl-L-Ser + H2S OASTL activity regulates not only Cys de novo synthesis but also its homeostasis Solanum tuberosum L-Cys + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.47 CS-A
-
 Solanum tuberosum
2.5.1.47 CS-B
-
 Solanum tuberosum
2.5.1.47 CSase A
-
 Solanum tuberosum
2.5.1.47 CSase B
-
 Solanum tuberosum
2.5.1.47 OAS-TL A
-
 Solanum tuberosum
2.5.1.47 OAS-TL B
-
 Solanum tuberosum
2.5.1.47 StOASTL A
-
 Solanum tuberosum
2.5.1.47 StOASTL B
-
 Solanum tuberosum