Literature summary extracted from

Lermontova, I.; Grimm, B.
Reduced activity of plastid protoporphyrinogen oxidase causes attenuated photodynamic damage during high-light compared to low-light exposure (2006), Plant J., 48, 499-510.

Application

EC Number	Application	Comment	Organism
1.3.3.4	additional information	light intensity-dependent degradation of reduced and oxidized porphyrins prevents severe photodynamic leaf damage, moreover, under high-light conditions, elevated contents of reduced and total low-molecular-weight antioxidants, which contribute to the protection against photosensitizing porphyrins	Nicotiana tabacum

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.3.3.4	additional information	transgenic lines, expression levels of PPOX I mRNA and protein and the cellular enzyme activities are reduced to similar extents in transgenic plants grown under low- or high-light conditions, more necrotic leaf lesions are surprisingly generated under low- than under high-light exposure	Nicotiana tabacum

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.3.3.4	acifluorfen	necrotic leaf lesions visible within the first hours of light exposure	Nicotiana tabacum
1.3.3.4	additional information	antisense RNA expression inhibits the formation of PPOX I in transgenic plants	Nicotiana tabacum

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.3.3.4	chloroplast	-	Nicotiana tabacum	9507	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.3.4	Nicotiana tabacum	O24163	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.3.3.4	leaf	-	Nicotiana tabacum	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.3.4	protoporphyrinogen-IX + 3 O2	-	Nicotiana tabacum	protoporphyrin-IX + 3 H2O2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.3.3.4	PPOX I	-	Nicotiana tabacum

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Release 2023.1 (January 2023)