EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.99.1 | additional information | the enzyme expression is not affected by methionine or choline intake in liver, overview | Rattus norvegicus | |
2.1.1.5 | choline | liver BHMT activity is 1.3fold higher in rats fed the methionine deficient diet containing choline than in rats fed the methionine-adequate diet containing supplemental choline | Rattus norvegicus | |
2.1.1.5 | L-methionine | independent of dietary choline, supplemental methionine increases hepatic BHMT activity by ca. 30% | Rattus norvegicus | |
2.1.1.5 | additional information | choline and methionine do not affect BHMT activity, mRNA expression and immunodetectable protein in the kidney | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.99.1 | additional information | the enzyme expression is not affected by methionine or choline intake in liver, overview | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.99.1 | additional information | Rattus norvegicus | the enzyme is responsible for the two-step choline oxidation to betaine together with the betaine-homocysteine methyltransferase | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.99.1 | Rattus norvegicus | - |
Sprague-Dawley rats | - |
2.1.1.5 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.99.1 | kidney | - |
Rattus norvegicus | - |
1.1.99.1 | liver | - |
Rattus norvegicus | - |
2.1.1.5 | kidney | - |
Rattus norvegicus | - |
2.1.1.5 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.99.1 | additional information | the enzyme is responsible for the two-step choline oxidation to betaine together with the betaine-homocysteine methyltransferase | Rattus norvegicus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.99.1 | CHDH | - |
Rattus norvegicus |
2.1.1.5 | betaine-homocysteine methyltransferase | - |
Rattus norvegicus |
2.1.1.5 | BHMT | - |
Rattus norvegicus |