EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.11.14 | isozyme GRK1 1A, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression of GRK proteins in HEK-293S cells | Danio rerio |
2.7.11.14 | isozyme GRK1B, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression of GRK proteins in HEK-293S cells | Danio rerio |
2.7.11.14 | isozyme GRK7 71, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in HEK-293S cells | Danio rerio |
2.7.11.14 | isozyme GRK72, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in HEK-293S cells | Danio rerio |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.14 | Mg2+ | - |
Danio rerio |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.14 | ATP + opsin | Danio rerio | the enzyme is involved in the opsin deactivation process, GRK subtypes play a role in phosphorylating non-visual opsins in the particular extraretinal tissues | ADP + phosphoopsin | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.14 | Danio rerio | Q1XHL7 | isozyme GRK7-2; gene grk7b, isozyme GRK 72 | - |
2.7.11.14 | Danio rerio | Q1XHM0 | isozyme GRK1A; isozyme GRK1A | - |
2.7.11.14 | Danio rerio | Q49HM9 | isozyme GRK7-1; gene grk7a, isozyme GRK7 71 | - |
2.7.11.14 | Danio rerio | Q49HN0 | isozyme GRK1B; isozyme GRK1B | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.14 | brain | GRK7-2, almost exclusively in the brain | Danio rerio | - |
2.7.11.14 | cone | - |
Danio rerio | - |
2.7.11.14 | eye | - |
Danio rerio | - |
2.7.11.14 | additional information | isozyme expression analysis, overview | Danio rerio | - |
2.7.11.14 | pineal gland | GRK1B and GRK7-2 are the dominant subtypes | Danio rerio | - |
2.7.11.14 | retina | rods and cones | Danio rerio | - |
2.7.11.14 | retinal rod | - |
Danio rerio | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.11.14 | additional information | - |
quantitative determination of GRK mRNA and protein in the eye, initial reaction velocities at 25°C and 30°C, overview | Danio rerio |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.14 | ATP + opsin | - |
Danio rerio | ADP + phosphoopsin | - |
? | |
2.7.11.14 | ATP + opsin | the enzyme is involved in the opsin deactivation process, GRK subtypes play a role in phosphorylating non-visual opsins in the particular extraretinal tissues | Danio rerio | ADP + phosphoopsin | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.14 | G protein-coupled receptor kinase | - |
Danio rerio |
2.7.11.14 | GRK1 | - |
Danio rerio |
2.7.11.14 | GRK7 | - |
Danio rerio |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.11.14 | 25 | 30 | assay at | Danio rerio |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.11.14 | 7.5 | - |
assay at | Danio rerio |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.14 | ATP | - |
Danio rerio |