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Literature summary extracted from

  • Sinclair, P.A.; Gilmore, W.J.; Lin, Z.; Lou, Y.; Squires, E.J.
    Molecular cloning and regulation of porcine SULT2A1: relationship between SULT2A1 expression and sulfoconjugation of androstenone (2006), J. Mol. Endocrinol., 36, 301-311.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.15 SULT2A1, DNA and amino acid sequence determination and analysis, relationship between SULT2A1 expression and sulfoconjugation of androstenone, quantitative expression analysis, overview, identification of nuclear receptors involved in regulating SULT2A1 Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.15 additional information SULT2A1 activity is negatively correlated with 5alpha-androstenone concentrations in fat, overview Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.15 cytosol
-
 Sus scrofa 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.15 3'-phosphoadenylyl sulfate + dehydroepiandrosterone Sus scrofa
-
 adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
 ?
2.8.2.15 additional information Sus scrofa SULT2A1 is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint, role of testicular and hepatic SULT2A1 activity on plasma 5alpha-androstenone sulfate levels, the accumulation of 5alpha-androstenone in adipose tissue, regulatory control of SULT2A1, SULT2A1 activity is negatively correlated with 5alpha-androstenone concentrations in fat, identification of nuclear receptors involved in regulating SULT2A1, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.15 Sus scrofa Q3S3F7 SULT2A1; mature Yorkshire boars, SULT2A1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.15 adipose tissue SULT2A1 Sus scrofa
-
2.8.2.15 liver SULT2A1 Sus scrofa
-
2.8.2.15 testis SULT2A1 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.15 3'-phosphoadenylyl sulfate + dehydroepiandrosterone
-
 Sus scrofa adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
 ?
2.8.2.15 additional information SULT2A1 is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint, role of testicular and hepatic SULT2A1 activity on plasma 5alpha-androstenone sulfate levels, the accumulation of 5alpha-androstenone in adipose tissue, regulatory control of SULT2A1, SULT2A1 activity is negatively correlated with 5alpha-androstenone concentrations in fat, identification of nuclear receptors involved in regulating SULT2A1, overview Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.15 hydroxysteroid sulfotransferase
-
 Sus scrofa
2.8.2.15 SULT2A1
-
 Sus scrofa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.2.15 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.15 7.4
-
 assay at Sus scrofa