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Literature summary extracted from

  • Seo, M.; Im, E.; Singh, D.; Rajkarnikar, A.; Kwon, H.; Hyun, C.; Suh, J.; Pyun, Y.; Kim, S.
    Characterization of D-glucose alpha -1-phosphate uridylyltransferase (VldB) and glucokinase (VldC) involved in validamycin biosynthesis of Streptomyces hygroscopicus var. limoneus KCCM 11405 (2006), J. Microbiol. Biotechnol., 16, 1311-1315.
No PubMed abstract available

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.214 Streptomyces hygroscopicus subsp. limoneus Q15JG5
-
-
2.7.1.214 Streptomyces hygroscopicus subsp. limoneus KCCM 11405 Q15JG5
-
-
2.7.7.9 Streptomyces hygroscopicus
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 recombinant protein. Enzyme is part of the validamycin A biosynthetic pathway
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2.7.7.9 Streptomyces hygroscopicus KCCM 11405
-
 recombinant protein. Enzyme is part of the validamycin A biosynthetic pathway
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.214 additional information enzyme shows glucokinase activity Streptomyces hygroscopicus subsp. limoneus ?
-
 ?
2.7.1.214 additional information enzyme shows glucokinase activity Streptomyces hygroscopicus subsp. limoneus KCCM 11405 ?
-
 ?
2.7.7.9 UTP + alpha-D-glucose 1-phosphate enzyme is specific for UTP Streptomyces hygroscopicus diphosphate + UDP-glucose
-
 ?
2.7.7.9 UTP + alpha-D-glucose 1-phosphate enzyme is specific for UTP Streptomyces hygroscopicus KCCM 11405 diphosphate + UDP-glucose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.214 vldC
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 Streptomyces hygroscopicus subsp. limoneus
2.7.7.9 VldB
-
 Streptomyces hygroscopicus

General Information

EC Number General Information Comment Organism
2.7.1.214 physiological function within the validamycin biosynthetic gene cluster, VldBC forms an operon of VldABC with VldA, the gene encoding 2-epi-5-epi-valiolone synthase Streptomyces hygroscopicus subsp. limoneus