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Literature summary extracted from

  • Khadzkou, K.; Buchwald, P.; Westin, G.; Dralle, H.; Akerstroem, G.; Hellman, P.
    25-hydroxyvitamin D3 1alpha-hydroxylase and vitamin D receptor expression in papillary thyroid carcinoma (2006), J. Histochem. Cytochem., 54, 355-361.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.15.18 25-hydroxyvitamin D + NADPH + O2 Homo sapiens
-
 1alpha,25-dihydroxyvitamin D + NADP+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.15.18 Homo sapiens
-
 female patients with papillary thyroid carcinoma
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.15.18 follicular thyroid cancer cell
-
 Homo sapiens
-
1.14.15.18 papillary thyroid cancer cell high enzyme and vitamin D receptor expression level, especially in regions of lymphocyte infiltration Homo sapiens
-
1.14.15.18 thyroid gland
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.15.18 25-hydroxyvitamin D + NADPH + O2
-
 Homo sapiens 1alpha,25-dihydroxyvitamin D + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.15.18 25-hydroxyvitamin D3 1alpha-hydroxylase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.15.18 NADPH
-
 Homo sapiens