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Literature summary extracted from

  • Lindermayr, C.; Saalbach, G.; Bahnweg, G.; Durner, J.
    Differential inhibition of Arabidopsis methionine adenosyltransferases by protein S-nitrosylation (2006), J. Biol. Chem., 281, 4285-4291.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.6 nitrosoglutathione reversibly inhibits the isozyme MAT1 via NO binding to Cys114, no inhibition of isozymes MAT2 and MAT3, molecular mechanism for S-nitrosylation of the enzyme Arabidopsis thaliana

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.5.1.6 K+
-
 Arabidopsis thaliana
2.5.1.6 Mg2+
-
 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.6 ATP + L-methionine + H2O Arabidopsis thaliana
-
 phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?
2.5.1.6 additional information Arabidopsis thaliana protein S-nitrosylation by NO represents a redox-based regulation mechanism playing a pivotal role in plants, MAT catalyzes the synthesis of the ethylene precursor S-adenosylmethionine and NO influences ethylene production in plants, the enzyme probably mediates the cross-talk between ethylene and NO signaling, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.6 Arabidopsis thaliana
-
 isozymes MAT1, MAT2, and MAT3
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.6 ATP + L-methionine + H2O
-
 Arabidopsis thaliana phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?
2.5.1.6 additional information protein S-nitrosylation by NO represents a redox-based regulation mechanism playing a pivotal role in plants, MAT catalyzes the synthesis of the ethylene precursor S-adenosylmethionine and NO influences ethylene production in plants, the enzyme probably mediates the cross-talk between ethylene and NO signaling, overview Arabidopsis thaliana ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.6 MAT
-
 Arabidopsis thaliana

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.5.1.6 35
-
 assay at Arabidopsis thaliana

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.5.1.6 8
-
 assay at Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
2.5.1.6 ATP
-
 Arabidopsis thaliana