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Literature summary extracted from

  • Yu, X.; Egner, P.A.; Wakabayashi, J.; Wakabayashi, N.; Yamamoto, M.; Kensler, T.W.
    Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-DELTA12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase (2006), J. Biol. Chem., 281, 26245-26252.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.1.74 expression in Escherichia coli Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.74 0.0096
-
 15-deoxy-DELTA12,14-prostaglandin J2 pH 7.2 Rattus norvegicus
1.3.1.74 0.24
-
 trans-2-pentenal pH 7.2 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.74 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.74 recombinant Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.74 15-deoxy-DELTA12,14-prostaglandin + NADPH
-
 Rattus norvegicus ?
-
 ?
1.3.1.74 15-deoxy-DELTA12,14-prostaglandin J2 + NADPH + H+
-
 Rattus norvegicus 12,13-dihydro-15-deoxy-DELTA12,14-prostaglandin J2 + NADP+
-
 r
1.3.1.74 trans-2-pentenal + NADPH
-
 Rattus norvegicus pentanal + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.74 alkenal/one oxidoreductase
-
 Rattus norvegicus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.3.1.74 0.308
-
 15-deoxy-DELTA12,14-prostaglandin J2 pH 7.2 Rattus norvegicus
1.3.1.74 0.97
-
 trans-2-pentenal pH 7.2 Rattus norvegicus
1.3.1.74 16.83
-
 trans-2-pentenal pH 7.2 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.74 NADPH
-
 Rattus norvegicus