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Literature summary extracted from

  • Al-Zoughool, M.; Talaska, G.
    4-Aminobiphenyl N-glucuronidation by liver microsomes: optimization of the reaction conditions and characterization of the UDP-glucuronosyltransferase isoforms (2006), J. Appl. Toxicol., 26, 524-532.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.17 alamethicin 0.05 mg//g protein, 8fold increase in activity Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.17 hecogenin competitive Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.17 0.0588
-
 4-aminobiphenyl
-
 Homo sapiens
2.4.1.17 0.2275
-
 4-aminobiphenyl
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.17 endoplasmic reticulum inner membrane Homo sapiens 5783
-
2.4.1.17 microsome
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.17 Homo sapiens O60656
-
-
2.4.1.17 Homo sapiens P22310
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.17 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.17 UDP-glucuronate + 4-aminobiphenyl
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.17 bilirubin-specific UDPGT isozyme 2
-
 Homo sapiens
2.4.1.17 HUG-BR2
-
 Homo sapiens
2.4.1.17 UDP-glucuronosyltransferase 1A4
-
 Homo sapiens
2.4.1.17 UDP-glucuronosyltransferase 1A9
-
 Homo sapiens
2.4.1.17 UDPGT
-
 Homo sapiens
2.4.1.17 UGT-1D
-
 Homo sapiens
2.4.1.17 UGT1-04
-
 Homo sapiens
2.4.1.17 UGT1-9
-
 Homo sapiens
2.4.1.17 UGT1.4
-
 Homo sapiens
2.4.1.17 UGT1.9
-
 Homo sapiens
2.4.1.17 UGT1A4
-
 Homo sapiens
2.4.1.17 UGT1A9
-
 Homo sapiens
2.4.1.17 UGT1D
-
 Homo sapiens