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Literature summary extracted from

  • Raizen, D.M.; Cullison, K.M.; Pack, A.I.; Sundaram, M.V.
    A novel gain-of-function mutant of the cyclic GMP-dependent protein kinase egl-4 affects multiple physiological processes in Caenorhabditis elegans (2006), Genetics, 173, 177-187.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.12 cGMP
-
 Caenorhabditis elegans

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.12 gene egl-4, expression analysis of wild-type and mutant enzymes Caenorhabditis elegans

Protein Variants

EC Number Protein Variants Comment Organism
2.7.11.12 additional information construction of the gain-of-function mutant egl-4 of PKG, mutation causes increased normal gene activity although it is associated with a reduced EGL-4 protein level, multiple phenotypes of egl-4 dominant mutants, detailed analysis, overview, isolation of egl-4 loss-of-function mutations in cis to ad450sd and of extragenic suppressors of ad450sd, overview Caenorhabditis elegans

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.12 Mg2+
-
 Caenorhabditis elegans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.12 additional information Caenorhabditis elegans PKG has an instructive signaling role to control many aspects of animal physiology ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.12 Caenorhabditis elegans
-
 several strains
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.12 additional information PKG has an instructive signaling role to control many aspects of animal physiology Caenorhabditis elegans ?
-
 ?
2.7.11.12 additional information structure-function relationship of PKG Caenorhabditis elegans ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.12 More structure-function relationship of PKG Caenorhabditis elegans

Synonyms

EC Number Synonyms Comment Organism
2.7.11.12 cyclic GMP-dependent protein kinase
-
 Caenorhabditis elegans
2.7.11.12 PKG
-
 Caenorhabditis elegans

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.12 ATP
-
 Caenorhabditis elegans