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Literature summary extracted from

  • Hirano, W.; Gotoh, I.; Uekita, T.; Seiki, M.
    Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway (2005), Genes Cells, 10, 565-574.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.13.11.53 E94A no activity Homo sapiens
1.13.11.54 E91A no activity Saccharomyces cerevisiae
1.13.11.54 E94A no activity Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.11.53 Ni2+
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.53 Homo sapiens
-
-
-
1.13.11.54 Homo sapiens
-
-
-
1.13.11.54 Saccharomyces cerevisiae
-
-
-
1.13.11.54 Saccharomyces cerevisiae Y700
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.53 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2
-
 Homo sapiens 3-(methylthio)propanoate + formate + CO
-
 ir
1.13.11.54 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2
-
 Homo sapiens 2-keto-4-methyl thiobutyrate + formate
-
 ir
1.13.11.54 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2
-
 Saccharomyces cerevisiae 2-keto-4-methyl thiobutyrate + formate
-
 ir
1.13.11.54 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2
-
 Saccharomyces cerevisiae Y700 2-keto-4-methyl thiobutyrate + formate
-
 ir

Synonyms

EC Number Synonyms Comment Organism
1.13.11.53 aci-reductone dioxygenase
-
 Homo sapiens
1.13.11.53 membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 MTCBP-1 Homo sapiens
1.13.11.54 aci-reductone dioxygenase
-
 Homo sapiens
1.13.11.54 aci-reductone dioxygenase
-
 Saccharomyces cerevisiae
1.13.11.54 MTCBP-1
-
 Homo sapiens
1.13.11.54 Ymr009p
-
 Saccharomyces cerevisiae