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Literature summary extracted from

  • Soldi, R.; Mandinova, A.; Venkataraman, K.; Hla, T.; Vadas, M.; Pitson, S.; Duarte, M.; Graziani, I.; Kolev, V.; Kacer, D.; Kirov, A.; Maciag, T.; Prudovsky, I.
    Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway (2007), Exp. Cell Res., 313, 3308-3318.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.91 expressed in the adenovirus shuttle vector pAdlox Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.91 cytosol
-
 Mus musculus 5829
-
2.7.1.91 membrane
-
 Mus musculus 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.91 Cu high affinity copper-binding protein Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.91 Mus musculus Q8CI15
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.91 G-Sepharose column chromatography Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.91 NIH-3T3 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.91 ATP + sphingosine
-
 Mus musculus ADP + sphingosine 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.91 SK1
-
 Mus musculus
2.7.1.91 sphingosine kinase 1
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.91 ATP
-
 Mus musculus