Literature summary extracted from

Raymond, M.N.; Bole-Feysot, C.; Banno, Y.; Tanfin, Z.; Robin, P.
Endothelin-1 inhibits apoptosis through a sphingosine kinase 1-dependent mechanism in uterine leiomyoma ELT3 cells (2006), Endocrinology, 147, 5873-5882.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.91	dimethylsphingosine	-	Rattus norvegicus
2.7.1.91	DL-threo-dihydrosphingosine	-	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.91	Rattus norvegicus	Q91V26	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.91	ELT-3 cell	-	Rattus norvegicus	-
2.7.1.91	uterine leiomyoma cell	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.91	ATP + sphingosine	-	Rattus norvegicus	ADP + sphingosine 1-phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.1.91	sphingosine kinase 1	-	Rattus norvegicus
2.7.1.91	SPHK1	-	Rattus norvegicus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.1.91	ATP	-	Rattus norvegicus

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Release 2023.1 (January 2023)