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Literature summary extracted from

  • Chen, J.; Liu, J.; Zhang, L.; Wu, G.; Hua, W.; Wu, X.; Sun, H.
    Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase (2006), Bioorg. Med. Chem. Lett., 16, 2915-2919.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.1 2,3-dihydroisooxazolyl oleanolic acid benzyl ester 50% inhibition at 0.0196 mM Oryctolagus cuniculus
2.4.1.1 2-hydroxymethenyl oleanonic acid benzyl ester 50% inhibition at 0.0063 mM Oryctolagus cuniculus
2.4.1.1 benzyl (2Z,5xi,8alpha,9xi,10alpha,14beta,17alpha,18alpha)-2-[[(2,4-dichlorobenzyl)oxy]imino]-3-oxoolean-12-en-28-oate 50% inhibition at 0.008 mM Oryctolagus cuniculus
2.4.1.1 oleanolic acid 50% inhibition at 0.014 mM Oryctolagus cuniculus
2.4.1.1 oleanolic acid 3-O-[(2E)-3-(4-chlorophenyl)acrylic acid] ester 50% inhibition at 0.0033 mM Oryctolagus cuniculus
2.4.1.1 oleanolic acid 3-O-[(2E)-3-(4-methoxyphenyl)acrylic acid] ester 50% inhibition at 0.0169 mM Oryctolagus cuniculus
2.4.1.1 oleanonic acid 50% inhibition at 0.0179 mM Oryctolagus cuniculus
2.4.1.1 oleanonic acid 2,3-oxadiazole 50% inhibition at 0.0112 mM Oryctolagus cuniculus
2.4.1.1 oleanonic acid 3-oxime 50% inhibition at 0.0208 mM Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.1 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.1 muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.1 glycogen + alpha-D-glucose 1-phosphate
-
 Oryctolagus cuniculus glycogen + phosphate
-
 ?