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Literature summary extracted from

  • Gresner, P.; Dolnik, M.; Waczulikova, I.; Bryszewska, M.; Sikurova, L.; Watala, C.
    Increased blood plasma hydrolysis of acetylsalicylic acid in type 2 diabetic patients: a role of plasma esterases (2006), Biochim. Biophys. Acta, 1760, 207-215.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.1.55 medicine higher aspirin esterase activity contributes to the lowered response of diabetic platelets to aspirin-mediated antiplatelet therapy Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.55 4-bis-nitrophenyl phosphate
-
 Homo sapiens
3.1.1.55 eserine selective for aspirin esterase II Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.55 acetylsalicylate + H2O Homo sapiens
-
 salicylate + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.55 Homo sapiens
-
-
-
3.1.1.55 Homo sapiens
-
 diabetes 2 patients and healthy individuals, higher activity in diabetes patients than in control individuals at pH 7.4, no differences at pH 5.5
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.55 blood
-
 Homo sapiens
-
3.1.1.55 blood higher aspirin esterase activity contributes to the lowered response of diabetic platelets to aspirin-mediated antiplatelet therapy Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.55 acetylsalicylate + H2O
-
 Homo sapiens salicylate + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.55 aspirin esterase
-
 Homo sapiens
3.1.1.55 aspirin esterase I albumin Homo sapiens
3.1.1.55 aspirin esterase II butyrylcholinesterase Homo sapiens