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Literature summary extracted from

  • Wang, F.Q.; Liu, J.; Dai, M.; Ren, Z.H.; Su, C.Y.; He, J.G.
    Molecular cloning and functional identification of a novel phenylacetyl-CoA ligase gene from Penicillium chrysogenum (2007), Biochem. Biophys. Res. Commun., 360, 453-458.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.2.1.30 overexpression in Escherichia coli Penicillium chrysogenum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.2.1.30 additional information the enzyme has a peroxisomal targeting signal on its C-terminal Penicillium chrysogenum
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.2.1.30 62638
-
 x * 62638, calculated from sequence Penicillium chrysogenum
6.2.1.30 64000
-
 x * 64000, SDS-PAGE Penicillium chrysogenum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.2.1.30 ATP + phenylacetate + CoA Penicillium chrysogenum PhlB might participate in the activation of phenylacetic acid during penicillin biosynthesis in Penicillium chrysogenum AMP + diphosphate + phenylacetyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.30 Penicillium chrysogenum A7KUK6
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.2.1.30
-
 Penicillium chrysogenum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.30 additional information the expression level of phlB in the penicillin producing medium supplemented with phenylacetic acid, the side chain precursor of penicillin G, is about 2.5fold higher than that in medium without phenylacetic acid Penicillium chrysogenum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.30 ATP + phenylacetate + CoA
-
 Penicillium chrysogenum AMP + diphosphate + phenylacetyl-CoA
-
 ?
6.2.1.30 ATP + phenylacetate + CoA PhlB might participate in the activation of phenylacetic acid during penicillin biosynthesis in Penicillium chrysogenum Penicillium chrysogenum AMP + diphosphate + phenylacetyl-CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
6.2.1.30 ? x * 64000, SDS-PAGE Penicillium chrysogenum
6.2.1.30 ? x * 62638, calculated from sequence Penicillium chrysogenum

Synonyms

EC Number Synonyms Comment Organism
6.2.1.30 phlB
-
 Penicillium chrysogenum

pI Value

EC Number Organism Comment pI Value Maximum pI Value
6.2.1.30 Penicillium chrysogenum calculated from sequence
-
 8.34