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Literature summary extracted from

  • Pallova, P.; Hercik, K.; Saskova, L.; Novakova, L.; Branny, P.
    A eukaryotic-type serine/threonine protein kinase StkP of Streptococcus pneumoniae acts as a dimer in vivo (2007), Biochem. Biophys. Res. Commun., 355, 526-530.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.1 expression of full-length and truncated StkP forms in Escherichia coli, overview Streptococcus pneumoniae

Protein Variants

EC Number Protein Variants Comment Organism
2.7.11.1 additional information deletion of the extracellular domain of StkP negatively affects the stability of a core kinase domain Streptococcus pneumoniae

General Stability

EC Number General Stability Organism
2.7.11.1 the extracellular domain of StkP is required for the stability of a core kinase domain, while the membrane-anchored kinase domain and the full-length form of StkP are stable and capable of autophosphorylation Streptococcus pneumoniae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.1 membrane membrane anchored kinase domain Streptococcus pneumoniae 16020
-
2.7.11.1 additional information subcellular localization of different epitope labeled forms of StkP, overview Streptococcus pneumoniae
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.1 Mg2+
-
 Streptococcus pneumoniae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.1 202000
-
 recombinant phosphorylated, full-length enzyme, native PAGE Streptococcus pneumoniae

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Streptococcus pneumoniae
-
 gene stkP
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.1 phosphoprotein StkP performs autophosphorylation Streptococcus pneumoniae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 additional information StkP performs autophosphorylation Streptococcus pneumoniae ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.1 dimer homodimerization in vivo, recombinant enzyme Streptococcus pneumoniae

Synonyms

EC Number Synonyms Comment Organism
2.7.11.1 eukaryotic-type serine/threonine protein kinase
-
 Streptococcus pneumoniae
2.7.11.1 Ser/Thr protein kinase
-
 Streptococcus pneumoniae
2.7.11.1 StkP
-
 Streptococcus pneumoniae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.11.1 22
-
 assay at room temperature Streptococcus pneumoniae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.11.1 7.5
-
 assay at Streptococcus pneumoniae

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.1 ATP
-
 Streptococcus pneumoniae