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Literature summary extracted from

  • Inagaki, Y.; Mitsutake, S.; Igarashi, Y.
    Identification of a nuclear localization signal in the retinitis pigmentosa-mutated RP26 protein, ceramide kinase-like protein (2006), Biochem. Biophys. Res. Commun., 343, 982-987.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.138 CERKL the point mutant enzyme CERKL does not phosphorylate ceramide or diacylglycerol and is localized in the nucleus Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.138 plasma membrane
-
 Homo sapiens 5886
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.138 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.138 anti-FLAG M2 affinity gel chromatography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.138 HEK-293 cell
-
 Homo sapiens
-
2.7.1.138 HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.138 ATP + ceramide
-
 Homo sapiens ADP + ceramide 1-phosphate
-
 ?
2.7.1.138 ATP + diacylglycerol
-
 Homo sapiens ADP + diacylglycerol 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.138 CERK
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.138 ATP
-
 Homo sapiens