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Literature summary extracted from

  • Bejar, P.; Villamarin, J.A.
    Catalytic subunit of cAMP-dependent protein kinase from a catch muscle of the bivalve mollusk Mytilus galloprovincialis: purification, characterization, and phosphorylation of muscle proteins (2006), Arch. Biochem. Biophys., 450, 133-140.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.11 inhibitor peptide PKI5-24 inhibits the catalytic subunit Mytilus galloprovincialis
2.7.11.11 additional information the two isoforms of the regulatory subunit inhibit the catalytic subunit Mytilus galloprovincialis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.11 37700
-
 catalytic subunit, gel filtration Mytilus galloprovincialis
2.7.11.11 40000
-
 1 * 40000, catalytic subunit, SDS-PAGE Mytilus galloprovincialis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.11 ATP + actin Mytilus galloprovincialis low activity ADP + phosphorylated actin
-
 ?
2.7.11.11 ATP + catchin Mytilus galloprovincialis low activity ADP + phosphorylated catchin
-
 ?
2.7.11.11 ATP + paramyosin Mytilus galloprovincialis low activity ADP + phosphorylated paramyosin
-
 ?
2.7.11.11 ATP + twitchin Mytilus galloprovincialis
-
 ADP + phosphorylated twitchin
-
 ?
2.7.11.11 additional information Mytilus galloprovincialis PKA plays a crucial role in the release of the catch state of molluskan muscles, mechanism, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.11 Mytilus galloprovincialis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.11 native enzyme from posterior adductor muscle by anion exchange chromatography, ultrafiltration, and gel filtration Mytilus galloprovincialis

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.11 posterior adductor muscle
-
 Mytilus galloprovincialis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.11 ATP + actin low activity Mytilus galloprovincialis ADP + phosphorylated actin
-
 ?
2.7.11.11 ATP + catchin low activity Mytilus galloprovincialis ADP + phosphorylated catchin
-
 ?
2.7.11.11 ATP + kemptide
-
 Mytilus galloprovincialis ADP + phospho-kemptide
-
 ?
2.7.11.11 ATP + paramyosin low activity Mytilus galloprovincialis ADP + phosphorylated paramyosin
-
 ?
2.7.11.11 ATP + twitchin
-
 Mytilus galloprovincialis ADP + phosphorylated twitchin
-
 ?
2.7.11.11 ATP + twitchin a high molecular mass protein associated with thick filaments, high activity Mytilus galloprovincialis ADP + phosphorylated twitchin
-
 ?
2.7.11.11 additional information PKA plays a crucial role in the release of the catch state of molluskan muscles, mechanism, overview Mytilus galloprovincialis ?
-
 ?
2.7.11.11 additional information no activity with myosin heavy chain and tropomyosin Mytilus galloprovincialis ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.11 monomer 1 * 40000, catalytic subunit, SDS-PAGE Mytilus galloprovincialis

Synonyms

EC Number Synonyms Comment Organism
2.7.11.11 PKA
-
 Mytilus galloprovincialis

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.11 ATP
-
 Mytilus galloprovincialis