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Literature summary extracted from
- Expression and characterization of recombinant human ADAMTS-13 (2004), Semin. Hematol., 41, 24-33.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.4.24.87 | medicine | ADAMTS-13 is deficient in congenital thrombotic thrombocytopenic purpura and inhibited in aquired thrombotic thrombocytopenic purpura. The availability of recombinant ADAMTS-13 raises the prospect of developing a recombinant substitution therapy to improve thrombotic thrombocytopenic purpura treatment and allows present diagnostic assays to be simplified | Homo sapiens |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.24.87 | - |
Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.87 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.87 | von Willebrand factor + H2O | cleavage of Tyr842-Met843 within the A2 domain, i.e. Tyr1605-Met1606 in von Willebrand factor UniProt Id P04275 | Homo sapiens | ? | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.87 | ADAMTS-13 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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