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Literature summary extracted from

  • Jiang, T.; Che, Q.; Lin, Y.; Li, H.; Zhang, N.
    Aldose reductase regulates TGF-beta1-induced production of fibronectin and type IV collagen in cultured rat mesangial cells (2006), Nephrology, 11, 105-112.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.21 expression in rat renal mesangial cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.21 additional information the recombinnat enzyme regulates TGF-beta1-induced production of fibronectin and type IV collagen in transformed cultured rat mesangial cells, detailed overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.21 aldose + NADPH + H+ Homo sapiens
-
alditol + NADP+
-
?
1.1.1.21 additional information Homo sapiens the enzyme regulates TGF-beta1-induced production of fibronectin and type IV collagen, overview ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.21 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.21 aldose + NADPH + H+
-
Homo sapiens alditol + NADP+
-
?
1.1.1.21 additional information the enzyme regulates TGF-beta1-induced production of fibronectin and type IV collagen, overview Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.21 aldose reductase
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.21 NADPH
-
Homo sapiens