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Literature summary extracted from

  • Goyal, N.; Duncan, R.; Selvapandiyan, A.; Debrabant, A.; Baig Mirza, S.; Nakhasi Hira, L.
    Cloning and characterization of angiotensin converting enzyme related dipeptidylcarboxypeptidase from Leishmania donovani (2006), Mol. Biochem. Parasitol., 145, 147-157.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.15.5 expression in Escherichia coli Leishmania donovani

Protein Variants

EC Number Protein Variants Comment Organism
3.4.15.5 H466A/H470A/Q467A mutation results in loss of activity Leishmania donovani

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.5 captopril significant inhibition at 200 mM. 47% inhibition at 50 nM Leishmania donovani

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.15.5 cytosol
-
 Leishmania donovani 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.15.5 additional information Leishmania donovani dipeptidylcarboxypeptidase plays a role in parasite nutrition ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.5 Leishmania donovani Q4KXL2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.5 amastigote
-
 Leishmania donovani
-
3.4.15.5 promastigote
-
 Leishmania donovani
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.5 additional information dipeptidylcarboxypeptidase plays a role in parasite nutrition Leishmania donovani ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.15.5 dipeptidylcarboxypeptidase
-
 Leishmania donovani
3.4.15.5 LdDCP
-
 Leishmania donovani