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Literature summary extracted from

  • Guimaraes, A.H.; Bertina, R.M.; Rijken, D.C.
    A new functional assay of thrombin activatable fibrinolysis inhibitor (2005), J. Thromb. Haemost., 3, 1284-1292.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.17.20 extracellular
-
 Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.17.20 Ca2+ required for enzyme activation Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.17.20 fibrin + H2O Homo sapiens anti-fibrinolytic activity fibrin + Lys
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.20 Homo sapiens
-
 genotypes 1040CC and 1040TT
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.20 blood
-
 Homo sapiens
-
3.4.17.20 blood plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.17.20 additional information
-
 assay development and optimization, overview Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.20 fibrin + H2O anti-fibrinolytic activity Homo sapiens fibrin + Lys
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.20 TAFI
-
 Homo sapiens
3.4.17.20 thrombin activatable fibrinolysis inhibitor
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.17.20 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.17.20 7.4
-
 assay at Homo sapiens