EC Number | Application | Comment | Organism |
---|---|---|---|
3.4.24.11 | medicine | neprilysin can reduce the size and number of Abeta deposits in a transgenic mouse model. Neprilysin gene transfer therapy or other methods to increase endogenous neprilysin activity have the potential to prevent the accumulation of the amyloid Abeta peptide and as such may be able to prevent or delay the onset of Alzheimer#s disease | Mus musculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.24.11 | phosphoramidon | - |
Mus musculus | |
3.4.24.11 | thiorphan | - |
Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.11 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.24.11 | brain | - |
Mus musculus | - |
3.4.24.11 | hippocampus | neurons | Mus musculus | - |
3.4.24.11 | neuron | hippocampal | Mus musculus | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.24.11 | NEP | - |
Mus musculus |