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Literature summary extracted from

  • Ono, S.; Hosokawa, M.; Miyashita, K.; Takahashi, K.
    Inhibition properties of dipeptides from salmon muscle hydrolysate on angiotensin I-converting enzyme (2006), Int. J. Food Sci. Technol., 41, 383-386.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 Ala-Trp IC50: 0.0064 mM, non-competitive Oryctolagus cuniculus
3.4.15.1 Ile-Trp IC50: 0.0047 mM, non-competitive Oryctolagus cuniculus
3.4.15.1 Leu-Phe IC50: 0.3832 mM, competitive Oryctolagus cuniculus
3.4.15.1 Leu-Trp IC50: 0.0174 mM, non-competitive Oryctolagus cuniculus
3.4.15.1 Met-Trp IC50: 0.0098 mM, non-competitive Oryctolagus cuniculus
3.4.15.1 Phe-Leu IC50: 0.0136 mM, non-competitive Oryctolagus cuniculus
3.4.15.1 Trp-Ala IC50: 0.2773 mM, competitive Oryctolagus cuniculus
3.4.15.1 Trp-Leu IC50: 0.0341 mM, non-competitive Oryctolagus cuniculus
3.4.15.1 Trp-Met IC50: 0.0986 mM, competitive Oryctolagus cuniculus
3.4.15.1 Trp-Val IC50: 0.5005 mM, competitive Oryctolagus cuniculus
3.4.15.1 Val-Trp IC50: 0.0025 mM, uncompetitive Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 lung
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 hippuryl-His-Leu + H2O
-
 Oryctolagus cuniculus hippuric acid + His-Leu
-
 ?

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.4.15.1 0.0025
-
 IC50: 0.0025 mM, uncompetitive Oryctolagus cuniculus Val-Trp
3.4.15.1 0.0047
-
 IC50: 0.0047 mM, non-competitive Oryctolagus cuniculus Ile-Trp
3.4.15.1 0.0064
-
 IC50: 0.0064 mM, non-competitive Oryctolagus cuniculus Ala-Trp
3.4.15.1 0.0098
-
 IC50: 0.0098 mM, non-competitive Oryctolagus cuniculus Met-Trp
3.4.15.1 0.0136
-
 IC50: 0.0136 mM, non-competitive Oryctolagus cuniculus Phe-Leu
3.4.15.1 0.0174
-
 IC50: 0.0174 mM, non-competitive Oryctolagus cuniculus Leu-Trp
3.4.15.1 0.0341
-
 IC50: 0.0341 mM, non-competitive Oryctolagus cuniculus Trp-Leu
3.4.15.1 0.0986
-
 IC50: 0.0986 mM, competitive Oryctolagus cuniculus Trp-Met
3.4.15.1 0.2773
-
 IC50: 0.2773 mM, competitive Oryctolagus cuniculus Trp-Ala
3.4.15.1 0.3832
-
 IC50: 0.3832 mM, competitive Oryctolagus cuniculus Leu-Phe
3.4.15.1 0.5005
-
 IC50: 0.5005 mM, competitive Oryctolagus cuniculus Trp-Val