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Literature summary extracted from
- Isolation of angiotensin converting enzyme (ACE) inhibitory flavonoids from Sedum sarmentosum (2004), Biol. Pharm. Bull., 27, 2035-2037.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.15.1 | captopril | 0.00002 mM | Rattus norvegicus |  |
| 3.4.15.1 | isorhamnetin-3-beta-glucopyranoside | IC50: 0.4089 mM | Rattus norvegicus | |
| 3.4.15.1 | kaempferol-3-alpha-arabinopyranoside | IC50: 0.3928 mM | Rattus norvegicus | |
| 3.4.15.1 | additional information | isolation of angiotensin converting enzyme (ACE) inhibitory flavonoids from Sedum sarmentosum | Rattus norvegicus | |
| 3.4.15.1 | quercetin 3-O-alpha-(6''-p-coumaroylglucosyl-beta -1,2-rhamnoside) | IC50: 0.351 mM | Rattus norvegicus | |
| 3.4.15.1 | quercetin-3-beta-glucopyranoside | IC50: 0.7088 mM | Rattus norvegicus | |
| 3.4.15.1 | quercetin-3-O-alpha-(6''-caffeoylglucosyl-beta-1,2-rhamnoside) | IC50: 0.1589 mM | Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | blood plasma | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.15.1 | hippuryl-His-Leu + H2O | - |
Rattus norvegicus | hippuric acid + His-Leu | - |
? | |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 3.4.15.1 | 0.1589 | - |
IC50: 0.1589 mM | Rattus norvegicus | quercetin-3-O-alpha-(6''-caffeoylglucosyl-beta-1,2-rhamnoside) | |
| 3.4.15.1 | 0.351 | - |
IC50: 0.351 mM | Rattus norvegicus | quercetin 3-O-alpha-(6''-p-coumaroylglucosyl-beta -1,2-rhamnoside) | |
| 3.4.15.1 | 0.3928 | - |
IC50: 0.3928 mM | Rattus norvegicus | kaempferol-3-alpha-arabinopyranoside | |
| 3.4.15.1 | 0.4089 | - |
IC50: 0.4089 mM | Rattus norvegicus | isorhamnetin-3-beta-glucopyranoside | |
| 3.4.15.1 | 0.7088 | - |
IC50: 0.7088 mM | Rattus norvegicus | quercetin-3-beta-glucopyranoside | |
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