Literature summary extracted from

Wheelock, C.E.; Eder, K.J.; Werner, I.; Huang, H.; Jones, P.D.; Brammell, B.F.; Elskus, A.A.; Hammock, B.D.
Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos (2005), Aquat. Toxicol., 74, 172-192.

Application

EC Number	Application	Comment	Organism
3.1.1.1	diagnostics	use of enzyme as a more sensitive biomarker for exposure to organophosphate than acetylcholinesterase. Enzyme is not suitable as a biomarker for pyrethroid exposure	Oncorhynchus tshawytscha

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.1.1	chlorpyrifos	significant inhibition of 56% and 79% after exposure to 0.0012 and 0.0073 mg/l, resp.	Oncorhynchus tshawytscha
3.1.1.1	additional information	exposure to esfenvalerate has little effect on enzyme activity	Oncorhynchus tshawytscha

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.1.1	Oncorhynchus tshawytscha	-	juvenile, after exposure to chlorpyrifos or esfenvalerate	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.1.1	liver	-	Oncorhynchus tshawytscha	-

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Release 2023.1 (January 2023)