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Literature summary extracted from

  • Yahr, T.L.; Vallis, A.J.; Hancock, M.K.; Barbieri, J.T.; Frank, D.W.
    ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system (1998), Proc. Natl. Acad. Sci. USA, 95, 13899-13904.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.6.1.1 Calmodulin no detectable stimulation of enzyme activity Pseudomonas aeruginosa
4.6.1.1 crude extract of cytosolic proteins from CHO cells at least 500fold increased adenylate cyclase activity Pseudomonas aeruginosa

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.6.1.1 expression in Escherichia coli Pseudomonas aeruginosa

Protein Variants

EC Number Protein Variants Comment Organism
4.6.1.1 D212N mutant with no detectable enzyme activity Pseudomonas aeruginosa
4.6.1.1 D214N mutant with no detectable enzyme activity Pseudomonas aeruginosa
4.6.1.1 K81M mutant with no detectable enzyme activity Pseudomonas aeruginosa
4.6.1.1 K88I mutant with no detectable enzyme activity Pseudomonas aeruginosa
4.6.1.1 r23ExoY mutant with histidine tag at carboxyl-terminal position, detectable enzyme activity Pseudomonas aeruginosa
4.6.1.1 rExoY mutant with histidine tag at amino-terminal position, detectable enzyme activity Pseudomonas aeruginosa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.6.1.1 41670
-
 predicted after nucleotide sequence analysis Pseudomonas aeruginosa

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.1 Pseudomonas aeruginosa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.6.1.1
-
 Pseudomonas aeruginosa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.1 ATP
-
 Pseudomonas aeruginosa 3',5'-cAMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.6.1.1 ExoY
-
 Pseudomonas aeruginosa