BRENDA - Enzyme Database show

Carbonic anhydrase IV and XIV knockout mice: roles of the respective carbonic anhydrases in buffering the extracellular space in brain

Shah, G.N.; Ulmasov, B.; Waheed, A.; Becker, T.; Makani, S.; Svichar, N.; Chesler, M.; Sly, W.S.; Proc. Natl. Acad. Sci. USA 102, 16771-16776 (2005)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.1
benzolamide
-
Mus musculus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.1
additional information
Mus musculus
carbonic anhydrase IV mediates buffering in the extracellular space in central nervous system
?
-
-
-
4.2.1.1
additional information
Mus musculus
carbonic anhydrase XIV mediates buffering in the extracellular space in central nervous system
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.1
Mus musculus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.1
brain
-
Mus musculus
-
4.2.1.1
central nervous system
-
Mus musculus
-
4.2.1.1
hippocampus
-
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.1
additional information
carbonic anhydrase IV mediates buffering in the extracellular space in central nervous system
666735
Mus musculus
?
-
-
-
-
4.2.1.1
additional information
carbonic anhydrase XIV mediates buffering in the extracellular space in central nervous system
666735
Mus musculus
?
-
-
-
-
Ki Value [mM]
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
4.2.1.1
0.0002
-
benzolamide
-
Mus musculus
4.2.1.1
0.0003
-
benzolamide
-
Mus musculus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.1
benzolamide
-
Mus musculus
Ki Value [mM] (protein specific)
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
4.2.1.1
0.0002
-
benzolamide
-
Mus musculus
4.2.1.1
0.0003
-
benzolamide
-
Mus musculus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.1
additional information
Mus musculus
carbonic anhydrase IV mediates buffering in the extracellular space in central nervous system
?
-
-
-
4.2.1.1
additional information
Mus musculus
carbonic anhydrase XIV mediates buffering in the extracellular space in central nervous system
?
-
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.1
brain
-
Mus musculus
-
4.2.1.1
central nervous system
-
Mus musculus
-
4.2.1.1
hippocampus
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.1
additional information
carbonic anhydrase IV mediates buffering in the extracellular space in central nervous system
666735
Mus musculus
?
-
-
-
-
4.2.1.1
additional information
carbonic anhydrase XIV mediates buffering in the extracellular space in central nervous system
666735
Mus musculus
?
-
-
-
-