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Literature summary extracted from

  • Shah, G.N.; Ulmasov, B.; Waheed, A.; Becker, T.; Makani, S.; Svichar, N.; Chesler, M.; Sly, W.S.
    Carbonic anhydrase IV and XIV knockout mice: roles of the respective carbonic anhydrases in buffering the extracellular space in brain (2005), Proc. Natl. Acad. Sci. USA, 102, 16771-16776.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.1 benzolamide
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.1 additional information Mus musculus carbonic anhydrase IV mediates buffering in the extracellular space in central nervous system ?
-
 ?
4.2.1.1 additional information Mus musculus carbonic anhydrase XIV mediates buffering in the extracellular space in central nervous system ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.1 brain
-
 Mus musculus
-
4.2.1.1 central nervous system
-
 Mus musculus
-
4.2.1.1 hippocampus
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.1 additional information carbonic anhydrase IV mediates buffering in the extracellular space in central nervous system Mus musculus ?
-
 ?
4.2.1.1 additional information carbonic anhydrase XIV mediates buffering in the extracellular space in central nervous system Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.1 carbonic anhydrase IV
-
 Mus musculus
4.2.1.1 carbonic anhydrase XIV
-
 Mus musculus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.2.1.1 0.0002
-
 benzolamide
-
 Mus musculus
4.2.1.1 0.0003
-
 benzolamide
-
 Mus musculus