Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • von Hertzen, L.S.; Giese, K.P.
    alpha-Isoform of Ca2+/calmodulin-dependent kinase II autophosphorylation is required for memory consolidation-specific transcription (2005), NeuroReport, 16, 1411-1414.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.17 Calmodulin dependent on Mus musculus

Protein Variants

EC Number Protein Variants Comment Organism
2.7.11.17 additional information deficiency in autophosphorylation in mice leads to impaired upregulation of an associative transcript, the nerve growth factor-inducible gene B messenger RNA, overview Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.17 Ca2+ dependent on Mus musculus
2.7.11.17 Mg2+
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.17 additional information Mus musculus CaMKII is required for gene transcription induced in the hippocampus by contextual fear conditioning, alphaCaMKII autophosphorylation is required for memory consolidation-specific transcription and formation of long term potentiation and memory, molecular mechanism, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.17 Mus musculus
-
 isozyme CaMKIIalpha
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.17 phosphoprotein the enzyme performs auophosphorylation Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.17 hippocampus
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.17 additional information the enzyme performs autophosphorylation Mus musculus ?
-
 ?
2.7.11.17 additional information CaMKII is required for gene transcription induced in the hippocampus by contextual fear conditioning, alphaCaMKII autophosphorylation is required for memory consolidation-specific transcription and formation of long term potentiation and memory, molecular mechanism, overview Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.17 alphaCaMKII
-
 Mus musculus
2.7.11.17 Ca2+/calmodulin-dependent kinase II
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.17 ATP
-
 Mus musculus