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Literature summary extracted from

  • Ben Ali, Y.; Carriere, F.; Verger, R.; Petry, S.; Muller, G.; Abousalham, A.
    Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases (2005), J. Lipid Res., 46, 994-1000.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.79 additional information Homo sapiens hormone-sensitive lipase may be the rate-limiting enzyme controlling the cellular catabolism of diacylglycerol in adipose tissue and that of cholesteryl esters in macrophage foam cells and steroidogenic tissues releasing the cholesterol required for adrenal steroidogenesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.79 Homo sapiens
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 recombinant
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Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.79 18
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.79 cholesteryl oleate + H2O
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 Homo sapiens cholesterol + oleate
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 ?
3.1.1.79 additional information hormone-sensitive lipase may be the rate-limiting enzyme controlling the cellular catabolism of diacylglycerol in adipose tissue and that of cholesteryl esters in macrophage foam cells and steroidogenic tissues releasing the cholesterol required for adrenal steroidogenesis Homo sapiens ?
-
 ?