EC Number | Crystallization (Comment) | Organism |
---|---|---|
4.6.1.1 | complex with 2-hydroxyestradiol and alpha/beta-methylene-ATP, 20-3 A resolution | Arthrospira platensis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.1 | 2-hydroxyestradiol | IC50 of about 2 microM | Arthrospira platensis | |
4.6.1.1 | 2-hydroxyestradiol | reversible inhibition of recombinant soluble enzyme in dose dependent manner, IC50 in low micromolar range, trans-membrane enzyme VII IC50 of about 2 microM | Homo sapiens | |
4.6.1.1 | 2-hydroxyestrone | reversible inhibition of recombinant soluble enzyme in dose dependent manner, IC50 in low micromolar range | Homo sapiens | |
4.6.1.1 | 4-hydroxyestradiol | - |
Arthrospira platensis | |
4.6.1.1 | 4-hydroxyestradiol | reversible inhibition of recombinant soluble enzyme in dose dependent manner, IC50 in low micromolar range | Homo sapiens | |
4.6.1.1 | additional information | not inhibitory: estrone and estrogen | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.6.1.1 | Arthrospira platensis | - |
- |
- |
4.6.1.1 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.6.1.1 | - |
Arthrospira platensis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.1 | ATP | - |
Homo sapiens | cAMP + diphosphate | - |
? | |
4.6.1.1 | ATP | - |
Arthrospira platensis | cAMP + diphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.6.1.1 | cyaC | - |
Arthrospira platensis |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
4.6.1.1 | 0.002 | - |
IC50 of about 2 microM | Arthrospira platensis | 2-hydroxyestradiol | |
4.6.1.1 | 0.002 | - |
reversible inhibition of recombinant soluble enzyme in dose dependent manner, IC50 in low micromolar range, trans-membrane enzyme VII IC50 of about 2 microM | Homo sapiens | 2-hydroxyestradiol |