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Literature summary extracted from

  • Morris, T.W.; Reed, K.E.; Cronan, J.E., Jr.
    Identification of the gene encoding lipoate-protein ligase A of Escherichia coli. Molecular cloning and characterization of the lplA gene and gene product (1994), J. Biol. Chem., 269, 16091-16100.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.1.20
-
 Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
6.3.1.20 additional information enzyme null mutant, normal transport of lipoic acid, but severe defect in incorporation and utilization of exogenously supplied lipoic acid and lipoic acid analogues. Strain is highly resistant to selenolipoate Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.1.20 38000
-
 x * 38000, calculated Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.3.1.20 Escherichia coli P32099
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.1.20
-
 Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.1.20 11.5
-
 37°C Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.1.20 ATP + DL-lipoic acid + protein
-
 Escherichia coli AMP + diphosphate + DL-lipoyl-protein
-
 ?

Subunits

EC Number Subunits Comment Organism
6.3.1.20 ? x * 38000, calculated Escherichia coli