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Literature summary extracted from

  • Chiou, S.Y.; Lai, C.Y.; Lin, L.Y.; Lin, G.
    Probing stereoselective inhibition of the acyl binding site of cholesterol esterase with four diastereomers of 2'-N-alpha-methylbenzylcarbamyl-1, 1'-bi-2-naphthol (2005), BMC Biochem., 6, 17.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.13 (1R, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
Bos taurus
3.1.1.13 (1R, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
Bos taurus
3.1.1.13 (1S, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
Bos taurus
3.1.1.13 (1S, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol
-
Bos taurus
3.1.1.13 (R)-2'-N-butylcarbamyl-1,1'-bi-naphthol
-
Bos taurus
3.1.1.13 (S)-2'-N-butylcarbamyl-1,1'-bi-naphthol
-
Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.13 Bos taurus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.13 p-nitrophenyl butyrate + H2O
-
Bos taurus p-nitrophenol + butyrate
-
?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.13 0.0002
-
(1R, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus
3.1.1.13 0.0005
-
(1R, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus
3.1.1.13 0.0008
-
(R)-2'-N-butylcarbamyl-1,1'-bi-naphthol pH 7.0, 25°C Bos taurus
3.1.1.13 0.0013
-
(S)-2'-N-butylcarbamyl-1,1'-bi-naphthol pH 7.0, 25°C Bos taurus
3.1.1.13 0.002
-
(1S, alphaR)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus
3.1.1.13 0.006
-
(1S, alphaS)-2'-N-alpha-methylbenzylcarbamyl-1,1'-bi-2-naphthol pH 7.0, 25°C Bos taurus