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Literature summary extracted from

  • Svartz, J.; Blomgran, R.; Hammarstrom, S.; Soderstrom, M.
    Leukotriene C4 synthase homo-oligomers detected in living cells by bioluminescence resonance energy transfer (2003), Biochim. Biophys. Acta, 1633, 90-95.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.4.1.20
-
 Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
4.4.1.20 LTCS(1-115) C-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(1-24) C-terminally truncated protein, gives no bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(1-58) C-terminally truncated protein, gives no bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(1-88) C-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(114-150) N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(23-115) C- and N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(23-150) N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(57-150) N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens
4.4.1.20 LTCS(87-150) N-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.4.1.20 endoplasmic reticulum
-
 Homo sapiens 5783
-
4.4.1.20 nuclear membrane
-
 Homo sapiens 31965
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.20 17000
-
 x * 17000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.20 leukotriene C4 Homo sapiens
-
 leukotriene A4 + glutathione
-
 r

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.20 Homo sapiens Q16873
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.20 HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.20 leukotriene A4 + glutathione
-
 Homo sapiens leukotriene C4
-
 r
4.4.1.20 leukotriene C4
-
 Homo sapiens leukotriene A4 + glutathione
-
 r

Subunits

EC Number Subunits Comment Organism
4.4.1.20 ? x * 17000, SDS-PAGE Homo sapiens
4.4.1.20 More forms homo-oligomers of LTCS fusion proteins with Renilla luciferase Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
4.4.1.20 leukotriene C4 synthase
-
 Homo sapiens
4.4.1.20 LTCS
-
 Homo sapiens