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Literature summary extracted from
- Localization of ferrochelatase in Plasmodium falciparum (2004), Biochem. J., 384, 429-436.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 4.98.1.1 | expression in Escherichia coli | Plasmodium falciparum |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.98.1.1 | apicoplast | - |
Plasmodium falciparum | 20011 | - |
| 4.98.1.1 | cytoplasm | parasite | Plasmodium falciparum | 5737 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.98.1.1 | 32500 | - |
monomer, truncated protein, SDS-PAGE | Plasmodium falciparum |
| 4.98.1.1 | 38000 | - |
monomer, partially purified enzyme, SDS-PAGE | Plasmodium falciparum |
| 4.98.1.1 | 42000 | - |
monomer, partially purified protein, SDS-PAGE | Plasmodium falciparum |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin + Fe2+ | Plasmodium falciparum | - |
protoheme + H+ | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | Plasmodium falciparum | Q8IFR0 | - |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.98.1.1 | partial | Plasmodium falciparum |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.98.1.1 | erythrocyte | - |
Plasmodium falciparum | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.98.1.1 | protoporphyrin + Fe2+ | - |
Plasmodium falciparum | protoheme + H+ | - |
? | |
| 4.98.1.1 | protoporphyrin IX + FeCl3 | pH 7.5, 37°C | Plasmodium falciparum | protoheme + HCl | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.98.1.1 | ferrochelatase | - |
Plasmodium falciparum |
| 4.98.1.1 | hFC | - |
Plasmodium falciparum |
| 4.98.1.1 | host red cell ferrochelatase | - |
Plasmodium falciparum |
| 4.98.1.1 | parasite genome-coded ferrochelatase | - |
Plasmodium falciparum |
| 4.98.1.1 | PfFC | - |
Plasmodium falciparum |
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