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Literature summary extracted from
- Species-specific expression of microsomal prostaglandin E synthase-1 and cyclooxygenases in male monkey reproductive organs (2004), Prostaglandins Leukot. Essent. Fatty Acids, 71, 233-240.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.99.3 | glutathione | - |
Rattus norvegicus |  |
| 5.3.99.3 | glutathione | - |
Sus scrofa | |
| 5.3.99.3 | glutathione | - |
Oryctolagus cuniculus | |
| 5.3.99.3 | glutathione | - |
Macaca fascicularis | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.3.99.3 | nucleus | - |
Macaca fascicularis | 5634 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.3.99.3 | 17000 | - |
SDS-PAGE | Macaca fascicularis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.99.3 | Macaca fascicularis | - |
- |
- |
| 5.3.99.3 | Oryctolagus cuniculus | - |
- |
- |
| 5.3.99.3 | Rattus norvegicus | - |
- |
- |
| 5.3.99.3 | Sus scrofa | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.3.99.3 | caput epididymis | weak enzyme expression | Rattus norvegicus | - |
| 5.3.99.3 | caput epididymis | weak enzyme expression | Sus scrofa | - |
| 5.3.99.3 | cauda epididymis | weak enzyme expression | Sus scrofa | - |
| 5.3.99.3 | cauda epididymis | weak enzyme expression, in the tubular epithelial cells of the caput and cauda | Rattus norvegicus | - |
| 5.3.99.3 | epididymis | in the tubular epithelial cells of the caput and cauda | Macaca fascicularis | - |
| 5.3.99.3 | additional information | seminal vesicular gland | Macaca fascicularis | - |
| 5.3.99.3 | prostate | - |
Sus scrofa | - |
| 5.3.99.3 | prostate | barely detectable | Rattus norvegicus | - |
| 5.3.99.3 | seminal vesicle | moderate enzyme expression | Rattus norvegicus | - |
| 5.3.99.3 | seminal vesicle | almost undetectable | Sus scrofa | - |
| 5.3.99.3 | testis | - |
Sus scrofa | - |
| 5.3.99.3 | testis | - |
Oryctolagus cuniculus | - |
| 5.3.99.3 | testis | spermatogonia, Sertoli cells and primary spermatocytes | Macaca fascicularis | - |
| 5.3.99.3 | testis | weak enzyme expression, Leydig cells, Sertoli cells, seminiferous tubules | Rattus norvegicus | - |
| 5.3.99.3 | vas deferens | in the epithelium from the proximal segment to the distal portion of the vas deferens and ampulla | Macaca fascicularis | - |
| 5.3.99.3 | vas deferens | strong enzyme expression, in the epithelium from the proximal segment to the distal portion of the vas deferens and ampulla | Rattus norvegicus | - |
| 5.3.99.3 | vas deferens | weak enzyme expression | Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.99.3 | Prostaglandin H2 | - |
Rattus norvegicus | Prostaglandin E2 | - |
? | |
| 5.3.99.3 | Prostaglandin H2 | - |
Sus scrofa | Prostaglandin E2 | - |
? | |
| 5.3.99.3 | Prostaglandin H2 | - |
Oryctolagus cuniculus | Prostaglandin E2 | - |
? | |
| 5.3.99.3 | Prostaglandin H2 | - |
Macaca fascicularis | Prostaglandin E2 | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.3.99.3 | mPGES-1 | - |
Rattus norvegicus |
| 5.3.99.3 | mPGES-1 | - |
Sus scrofa |
| 5.3.99.3 | mPGES-1 | - |
Oryctolagus cuniculus |
| 5.3.99.3 | mPGES-1 | - |
Macaca fascicularis |
| 5.3.99.3 | prostaglandin E synthase-1 | - |
Rattus norvegicus |
| 5.3.99.3 | prostaglandin E synthase-1 | - |
Sus scrofa |
| 5.3.99.3 | prostaglandin E synthase-1 | - |
Oryctolagus cuniculus |
| 5.3.99.3 | prostaglandin E synthase-1 | - |
Macaca fascicularis |
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Release 2023.1 (January 2023)
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