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Literature summary extracted from

  • Levitan, A.; Trebitsh, T.; Kiss, V.; Pereg, Y.; Dangoor, I.; Danon, A.
    Dual targeting of the protein disulfide isomerase RB60 to the chloroplast and the endoplasmic reticulum (2005), Proc. Natl. Acad. Sci. USA, 102, 6225-6230.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.4.1 expression of GFP- or ORF-tagged RB60, wild-type and deletion mutants, in vitro protein synthesis using the T3 TNT-coupled reticulocyte lysate system Chlamydomonas reinhardtii

Protein Variants

EC Number Protein Variants Comment Organism
5.3.4.1 additional information construction of deletion mutants DELTA28RB60, L28 and L50 Chlamydomonas reinhardtii

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.4.1 chloroplast RB60 contains an N-terminal sequence of 50 amino acids that are sufficient for chloroplast and enodplasmic reticulum targeting, after translocation to the ER the leader sequence is cleaved while it remains intact after import into chloroplasts Chlamydomonas reinhardtii 9507
-
5.3.4.1 endoplasmic reticulum the enzyme contains a C-terminal endoplasmic reticulum retention signal, RB60 contains an N-terminal leader sequence of 50 amino acids that are sufficient for chloroplast and enodplasmic reticulum targeting, after translocation to the ER the leader sequence is cleaved while it remains intact after import into chloroplasts Chlamydomonas reinhardtii 5783
-
5.3.4.1 microsome
-
 Chlamydomonas reinhardtii
-
-
5.3.4.1 additional information dual localization of RB60 via two different conserved transport mechanisms, overview Chlamydomonas reinhardtii
-
-
5.3.4.1 thylakoid membrane
-
 Chlamydomonas reinhardtii 42651
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.4.1 additional information Chlamydomonas reinhardtii RB60 is an atypical PDI that functions as a member of a redox regulatory protein complex controlling translation in the chloroplast, the enzyme is essential in the endoplasmic reticulum ?
-
 ?
5.3.4.1 additional information Chlamydomonas reinhardtii 2137a RB60 is an atypical PDI that functions as a member of a redox regulatory protein complex controlling translation in the chloroplast, the enzyme is essential in the endoplasmic reticulum ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.4.1 Chlamydomonas reinhardtii
-
-
-
5.3.4.1 Chlamydomonas reinhardtii 2137a
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.4.1 additional information RB60 is an atypical PDI that functions as a member of a redox regulatory protein complex controlling translation in the chloroplast, the enzyme is essential in the endoplasmic reticulum Chlamydomonas reinhardtii ?
-
 ?
5.3.4.1 additional information RB60 is an atypical PDI that functions as a member of a redox regulatory protein complex controlling translation in the chloroplast, the enzyme is essential in the endoplasmic reticulum Chlamydomonas reinhardtii 2137a ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.3.4.1 protein disulfide isomerase
-
 Chlamydomonas reinhardtii
5.3.4.1 RB60
-
 Chlamydomonas reinhardtii