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Literature summary extracted from

  • Zhang, Z.; Alfonta, L.; Tian, F.; Bursulaya, B.; Uryu, S.; King, D.S.; Schultz, P.G.
    Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells (2004), Proc. Natl. Acad. Sci. USA, 101, 8882-8887.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
6.1.1.2 V144P mutant selectively aminoacylates the cognate mutant opal suppressor tRNATrp(UCA) with 5-hydroxy-L-tryptophan and not with any endogenous amino acid Bacillus subtilis

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.2 Bacillus subtilis
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.2 ATP + 5-hydroxy-L-tryptophan + tRNATrp mutant enzyme V144P selectively aminoacylates the cognate mutant opal suppressor tRNATrp(UCA) with 5-hydroxy-L-tryptophan and not with any endogenous amino acid Bacillus subtilis AMP + diphosphate + 5-hydroxy-L-tryptophan-tRNATrp
-
 ?
6.1.1.2 ATP + L-tryptophan + tRNATrp BsTRpRS charges only the cognate mutant opal suppressor tRNATrp(UCA) and not endogenous mammalian tRNAs Bacillus subtilis AMP + diphosphate + L-tryptophan-tRNATrp
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.2 BsTRpRS
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 Bacillus subtilis