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Literature summary extracted from

  • Benter, I.F.; Juggi, J.S.; Khan, I.; Yousif, M.H.M.; Canatan, H.; Akhtar, S.
    Signal transduction mechanisms involved in cardiac preconditioning: role of Ras-GTPase, Ca2+/calmodulin-dependent protein kinase II and epidermal growth factor receptor (2005), Mol. Cell. Biochem., 268, 175-183.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.1 AG1478 inhibition of epidermal growth factor receptor tyrosine kinase Rattus norvegicus
2.7.10.1 FPT III inhibition of epidermal growth factor receptor tyrosine kinase Rattus norvegicus
2.7.10.1 genistein inhibition of epidermal growth factor receptor tyrosine kinase Rattus norvegicus
2.7.10.1 KN93 inhibition of epidermal growth factor receptor tyrosine kinase Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.1 additional information Rattus norvegicus the enzyme epidermal growth factor receptor tyrosine kinase is involved in signal transduction in cardiac preconditioning, mechanisms, enzyme inhibition is cardioprotective ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 heart
-
 Rattus norvegicus
-
2.7.10.1 ventriculus left Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.1 additional information the enzyme epidermal growth factor receptor tyrosine kinase is involved in signal transduction in cardiac preconditioning, mechanisms, enzyme inhibition is cardioprotective Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 EGFR tyrosine kinase
-
 Rattus norvegicus
2.7.10.1 epidermal growth factor receptor tyrosine kinase
-
 Rattus norvegicus